Solid State Characterization of Pharmaceuticals

Solid form selection is a critical part of the development of a pharmaceutical compound. The presence of a crystalline drug substance provides improved bulk properties, whereas the use of a salt of a pharmaceutical compound can provide enhanced properties such as increased dissolution rate. Owing to different crystal structures, polymorphic forms of a compound have different physical and chemical properties, which can affect the biopharmaceutical properties of a pharmaceutical compound. The selection of the optimum salt and physical form for development utilises a wide range of analytical procedures and laboratory skills. This book provides an up-to-date review of the current techniques used to characterise pharmaceutical solids. It will serve as a vital resource for analysts, and essential reading for scientists involved in solid form selection.Storey, Richard is the author of 'Solid State Characterization of Pharmaceuticals ', published 2007 under ISBN 9781405134941 and ISBN 1405134941.