Feline Immunology and Immunodeficiency

The discovery of feline immunodeficiency virus (FIV) has heightened interest in feline immunology, with FIV emerging as an animal model for HIV infection in humans. Researchers in the AIDS field and veterinary researchers alike will find this compilation of state-of-the-art studies on the principal small animal model for AIDS essential reading. Willett and Jarrett provide a much needed overview of feline immunology and immunodeficiency. Subjects covered include basic immunology of the cat, including surface marker expression, the T-cell receptor, MHC, cytokines, and immunoglobulins. Many aspects of FIV pathogenesis are also covered including viral tropism, the effects of infection on the immune system, genomic structure and variation, epitope mapping of viral proteins, FIV-induced CTL, and vaccination against FIV infection. Researchers in the AIDS field and veterinary researchers alike will find this essential reading: it is a compilation of state-of-the-art studies on the principal small animal model for AIDS.Willett, B. J. is the author of 'Feline Immunology and Immunodeficiency' with ISBN 9780198547778 and ISBN 0198547773.