Classics in Stereoselective Synthesis

Stereoselective or asymmetric synthesis of organic molecules ideally leads to one of several possible steric structures of a target molecule, which is most important for economical multistep syntheses of natural products, drugs, and fine chemicals, among others, that show activity only in a certain steric modification. Providing an excellent compilation of the most important and useful methods, this book features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the users' own synthesis. From the contents: * Alkylations * Aldol additions * Allyl metal additions * C=O additions and reductions * Epoxides, olefin epoxidation, epoxide transformations * Dihydroxylation, aminohydroxylation * Hydroboration * C=C reductions and additions * Cycloadditions, rearrangements * C=N additions andreductions * Chiral acetals * Macrocyclic stereocontrol * Olefinations The authors adopt a novel approach in not attempting to present this rapidly developing area in its entirety, but to distill the truly groundbreaking reactions that should be in the repertoire of every synthetic organic chemist.Carreira, Erick M. is the author of 'Classics in Stereoselective Synthesis' with ISBN 9783527299669 and ISBN 3527299661.